Exposure to elevated glucocorticoid during development primes altered transcriptional responses to acute stress in adulthood
Summary: Early life stress (ELS) is a major risk factor for developing psychiatric disorders, with glucocorticoids (GCs) implicated in mediating its effects in shaping adult phenotypes.In this process, exposure to high levels of developmental GC (hdGC) is thought to induce molecular changes Tub Sealing Gasket that prime differential adult responses